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Pelizaeus–Merzbacher disease is an X-linked neurological disorder that damages oligodendrocytes in the central nervous system. It is caused by mutations in proteolipid protein 1 (PLP1), a major myelin protein. It is characterized by hypomyelination and belongs to a group of genetic diseases referred to as leukodystrophies.[2]

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Pelizaeus-Merzbacher disease (PMD) is a rare, progressive, degenerative central nervous system disorder in which coordination, motor abilities, and intellectual function deteriorate. The disease is one of a group of gene-linked disorders known as the leukodystrophies, which affect growth of the myelin sheath -- the fatty covering that wraps around and protects nerve fibers in the brain.

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Pelizaeus-Merzbacher disease (PMD) can now be defined as an X-linked recessive leukodystrophy that is caused by a mutation in the proteolipid protein (PLP) gene on chromosome Xq22. The most common mutation is gene duplication followed in frequency by missense mutations, insertions, and deletions.

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Die Pelizaeus-Merzbacher-Krankheit ist eine seltene angeborene Erkrankung des zentralen Nervensystems. Bei dieser Erkrankung aus der Gruppe der Leukodystrophien tritt eine Störung der Myelinisierung auf, durch die eine Vielzahl von Symptomen verursacht werden können. Die Krankheit ist nach den Erstbeschreibern Friedrich Christoph Pelizaeus ...

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Pelizaeus–Merzbacher disease Medical » Medical Physics Add to My List Edit this Entry Rate it: (0.00 / 0 votes) Translation Find a translation for Pelizaeus–Merzbacher disease in other languages: Select another language: - Select - (Chinese ...

Grave site information of Georg Merzbacher (13 Feb 1896 - 16 Jun 1975) at Hauptfriedhof Würzburg in Würzburg, Würzburg, Bayern, Germany from BillionGraves

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Grave site information of Friedrich Merzbacher (5 May 1923 - 22 Apr 1982) at Hauptfriedhof Würzburg in Würzburg, Würzburg, Bayern, Germany from BillionGraves

Eugen Merzbacher was an American physicist. Merzbacher was born in Berlin and emigrated in 1935 with his family from Germany to Turkey, where his father worked as a chemist. He received his licentiate from University of Istanbul in Turkey in 1943 and taught

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Eugen Merzbacher (April 9, 1921 – June 6, 2013) was an American physicist. Merzbacher was born in Berlin ing a Jew, he emigrated in 1935 with his family from Germany to Turkey, where his father worked as a chemist.He received his licentiate from University of Istanbul in Turkey in 1943 and taught high school in Ankara for the next four years.

Rolf Merzbacher besuchte seit 1937 in der Schweizer Nachbarstadt Kreuzlingen die Primarschule und war dort bei einer Schweizer Familie untergebracht. Werner Merzbacher durfte am 16. Februar 1939 mit einer Gruppe jüdischer Kinder in die Schweiz einreisen und wurde in …

Pelizaeus–Merzbacher disease (PMD) is the prototypic hypomyelinating disorder that was described at the end of the 19th century (Pelizaeus, 1885; Merzbacher, 1910). It is an X-linked recessive disease caused by rearrangements or mutations in the gene encoding proteolipid protein 1, PLP1 (Gencic et al., 1989 ; Hudson et al., 1989 ), a major component of myelin in the central nervous system.

Translation for ''Erzbrecher'' in the free German-English dictionary and many other English translations. Did you know? All our dictionaries are bidirectional, meaning that you can look up words in both languages at the same time.